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1.
Clinical Medicine of China ; (12): 394-397, 2022.
Article in Chinese | WPRIM | ID: wpr-956388

ABSTRACT

Portal vein thrombosis(PVT) plays a crucial role in pathogenesis of portal hypertension. Thrombus located in portal trunk or hepatic branches, which can expand into splenic vein or mesenteric vein, causing severe symptoms. Hypercoagulation state and portal haemodynamic disorder increase the risk of PVT in pregnancy. Anticoagulation is the basic treatment of pregnancy complicated with acute PVT, which can not only inhibit the progress of portal vein thrombosis, but also promote the recanalization of the lumen and improve the prognosis of patients. Anticoagulation should be administered for at least 6 moths according to available guidelines. Based on reliable efficacy and superior safety, low-molecular-weight-heparin remains the first choice of anticoagulant therapy. Vitamin K antagonists and direct oral anticoagulants are not recommended for PVT in pregnancy.

2.
International Journal of Surgery ; (12): 730-734, 2022.
Article in Chinese | WPRIM | ID: wpr-989369

ABSTRACT

Aortoiliac occlusive disease is a group of ischemic disease caused by stenosis or occlusion of infrarenal aorta and iliac artery. Gluteus or lower extremity intermittent claudication and even limb-threatening ischemia are most common symptoms. With the development of endovascular devices and techniques, therapeutic options of complex lesions have changed from open surgery to endovascular treatment, which have the advantages including satisfied patency rate, less perioperative complications and fast recovery. This article will review and summarize stent implantation choices and techniques for endovascular treatment in aortoiliac occlusive disease.

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